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Table 3 Association between PINI and overall survival of patients with colorectal cancer

From: Prognostic significance of preoperative prognostic immune and nutritional index in patients with stage I–III colorectal cancer

PINI

Model a

P value

Model b

P value

Model c

P value

Continuous (per SD)

0.839 (0.777,0.906)

< 0.001

0.824 (0.759,0.895)

< 0.001

0.833 (0.761,0.912)

< 0.001

Cutoff value

 

< 0.001

 

< 0.001

 

< 0.001

 C1 (~ 2.85)

ref

 

ref

 

ref

 

 C2 (2.85~)

0.574 (0.474,0.694)

 

0.56 (0.459,0.682)

 

0.561 (0.453,0.696)

 

Quartiles

      

 Q1 (~ 2.84)

ref

 

ref

 

ref

 

 Q2 (2.84 ~ 3.15)

0.632 (0.496,0.805)

< 0.001

0.592 (0.463,0.757)

< 0.001

0.592 (0.458,0.765)

< 0.001

 Q3 (3.15 ~ 3.38)

0.558 (0.432,0.72)

< 0.001

0.584 (0.45,0.759)

< 0.001

0.575 (0.436,0.757)

< 0.001

 Q4 (3.38~)

0.547 (0.422,0.708)

< 0.001

0.523 (0.402,0.682)

< 0.001

0.534 (0.402,0.708)

< 0.001

p for trend

 

< 0.001

 

< 0.001

 

< 0.001

  1. Model a: No adjusted
  2. Model b: Adjusted for sex, age, T stage and N stage
  3. Model c: Adjusted for sex, age, BMI, hypertension, diabetes, T stage, N stage, tumor location, tumor size, perineural invasion, vascular invasion, macroscopic type, differentiation, surgical approach, CEA level, radiotherapy, and chemotherapy