Table 1 The relationships between the PINI and clinicopathological features of patients with colorectal cancer

Sex (Man)

821 (63.0)

236 (70.7)

585 (60.3)

0.001

Age (mean (SD))

58.31 (13.00)

61.26 (13.53)

57.30 (12.66)

< 0.001

Age (≥ 60)

655 (50.2)

205 (61.4)

450 (46.4)

< 0.001

BMI (median [IQR])

22.07 (20.00, 24.46)

21.50 (19.15, 23.42)

22.43 (20.21, 24.85)

< 0.001

BMI

< 0.001

 Low (< 18.5)

161 (12.3)

64 (19.2)

97 (10.0)

 Normal (18.5–24.9)

762 (58.4)

204 (61.1)

558 (57.5)

 High (≥ 25)

381 (29.2)

66 (19.8)

315 (32.5)

Hypertension (Yes)

218 (16.7)

61 (18.3)

157 (16.2)

0.428

Diabetes (Yes)

82 (6.3)

23 (6.9)

59 (6.1)

0.696

T stage

0.047

 T1

364 (27.9)

88 (26.3)

276 (28.5)

 T2

690 (52.9)

181 (54.2)

509 (52.5)

 T3

250 (19.2)

65 (19.5)

185 (19.1)

N stage

0.246

 N0

765 (58.7)

204 (61.1)

561 (57.8)

 N1

351 (26.9)

91 (27.2)

260 (26.8)

 N2

188 (14.4)

39 (11.7)

149 (15.4)

TNM stage

0.644

 Stage I

284 (21.8)

74 (22.2)

210 (21.6)

 Stage II

481 (36.9)

129 (38.6)

352 (36.3)

 Stage III

539 (41.3)

131 (39.2)

408 (42.1)

Perineural invasion (Yes)

125 (9.6)

30 (9.0)

95 (9.8)

0.744

Vascular invasion (Yes)

210 (16.1)

46 (13.8)

164 (16.9)

0.208

Macroscopic type

0.011

Protrude type

376 (28.8)

112 (33.5)

264 (27.2)

Infiltrating type

99 (7.6)

32 (9.6)

67 (6.9)

Ulcerative type

829 (63.6)

190 (56.9)

639 (65.9)

Differentiation (Poor)

157 (12.0)

44 (13.2)

113 (11.6)

0.522

Tumor location (Rectal)

685 (52.5)

124 (37.1)

561 (57.8)

< 0.001

Tumor size (median [IQR])

4.50 (3.50, 6.00)

5.50 (4.00, 7.50)

4.00 (3.00, 5.00)

< 0.001

CEA (High)

497 (38.1)

161 (48.2)

336 (34.6)

< 0.001

Surgical method (Endoscopic)

796 (61.0)

155 (46.4)

641 (66.1)

< 0.001

Operation time (median [IQR])

186.00 (148.00, 242.50)

196.50 (163.25, 261.50)

182.00 (143.00, 236.50)

< 0.001

Intraoperative blood loss (median [IQR])

100.00 (50.00, 200.00)

100.00 (80.00, 200.00)

100.00 (50.00, 200.00)

< 0.001

Radiotherapy (Yes)

124 (9.5)

17 (5.1)

107 (11.0)

0.002

Chemotherapy (Yes)

581 (44.6)

138 (41.3)

443 (45.7)

0.183

Death (Yes)

457 (35.0)

168 (50.3)

289 (29.8)

< 0.001

Hospital stays (median [IQR])

17.00 (11.00, 21.00)

19.00 (15.00, 23.75)

16.00 (10.00, 20.00)

< 0.001

Hospitalization cost (median [IQR])

49239.24 (44407.25, 55607.16)

51692.23 (45199.72, 59809.63)

48729.73 (44257.75, 54564.84)

< 0.001