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Table 2 Predictive factors of toxicity in the population receiving hypofractionated therapy (N = 308)

From: Acute skin toxicity of conventional fractionated versus hypofractionated radiotherapy in breast cancer patients receiving regional node irradiation: the real-life prospective multicenter HYPOBREAST cohort

 

Bivariate analysis

Final multivariate model*

OR, 95% CI

p

OR, 95% CI

p

Breast (vs chest wall) ∆

4.47 [1.33;15.06]

0.02

5.74 [1.64;20.04]

0.006

Technique IMRT (vs 3D) ∆

0.47 [0.20;1.08]

0.07

0.30 [0.14;0.80]

0.014

Axillary irradiation ∆

2.41 [0.83;6.94]

0.10

  

Energy (high vs standard) ∆

2.20 [0.96;5.08]

0.06

  

Electrons

0.47 [0.36;8.13]

0.50

  

Tumor bed boost

1.08 [0.52;2.27]

0.83

  

Smoking

0.92 [0.20;4.25]

0.92

  
  1. OR odds ratio, CI confidence interval, IMRT Intensity Modulated Radiation Therapy, 3D 3D conformal
  2. ∆ Included in the full multivariate analysis
  3. *Final model after backward selection
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BMC Cancer

ISSN: 1471-2407

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