Table 4 Radiographic and clinical response summary
Parameter | N = 21 |
|---|---|
Best observed radiographic response, n (%) | |
Complete response (CR) | 0 (0) |
Partial response (PR) | 4 (19) |
Stable disease (SD) | 12 (57) |
Progressive disease (PD) | 5 (24) |
Overall response rate (ORR), n (%) | 4 (19) |
Disease control rate (DCR), n (%) | 16 (76) |
Time to maximum response, median (range), months | 2.1 (1.5–7) |
Hepatic progression, n (%) | 11 (52) |
Extrahepatic progression, n (%) | 13 (62) |
Extrahepatic disease site | |
Lungs | 9 |
Lymph nodes | 6 |
Peritoneum | 5 |
Ovary | 2 |
Primary tumor | 2 |
PFS, median (range), months | |
Overall | 3.8 (0.7–21.2) |
Hepatic | 4.4 (1.5–21.2) |
Extrahepatic | 3.6 (0.7–18.5) |
OS, median (range), months | 6.4 (3–36.8) |