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Table 2 Comparative analysis of the discrimination of each biomarker for all-cause mortality in patients with cancer

From: A novel inflammation-nutrition biomarker score for predicting prognosis of patients with cancer: results from a multicenter study

Discrimination Ability

C-statistic

C-statistics

cNRI

IDI

Difference

p value

Difference

p value

Difference

p value

INS

0.663(0.651,0.674)

Ref

 

Ref

 

Ref

 

LCR

0.652(0.640,0.665)

-0.044(-0.051, -0.037)

 < 0.001

-0.208(-0.257, -0.052)

 < 0.001

-0.022(-0.034, -0.009)

 < 0.001

CAR

0.649(0.636,0.661)

-0.048(-0.055, -0.041)

 < 0.001

-0.105(-0.242, -0.058)

 < 0.001

-0.028(-0.040, -0.017)

 < 0.001

ALI

0.643(0.630,0.655)

-0.051(-0.059, -0.041)

 < 0.001

-0.273(-0.322, -0.225)

 < 0.001

-0.054(-0.072, -0.039)

 < 0.001

NRI

0.623(0.610,0.636)

-0.080(-0.089, -0.071)

 < 0.001

-0.310(-0.348, -0.214)

 < 0.001

-0.083(-0.100, -0.064)

 < 0.001

mGNRI

0.639(0.627,0.652)

-0.023(-0.031, -0.014)

 < 0.001

-0.126(-0.196, -0.020)

 < 0.001

-0.029(-0.052, -0.007)

0.020

NLR

0.623(0.610,0.636)

-0.040(-0.051, -0.029)

 < 0.001

-0.316(-0.361, -0.266)

 < 0.001

-0.113(-0.134, -0.089)

 < 0.001

mGPS

0.609(0.598,0.620)

-0.054(-0.063, -0.045)

 < 0.001

-0.102(-0.257, -0.061)

 < 0.001

-0.044(-0.061, -0.030)

 < 0.001

SII

0.608(0.596,0.621)

-0.054(-0.067, -0.042)

 < 0.001

-0.318(-0.359, -0.268)

 < 0.001

-0.109(-0.131, -0.087)

 < 0.001

LCS

0.598(0.587,0.608)

-0.065(-0.076, -0.054)

 < 0.001

-0.182(-0.231, -0.072)

0.090

-0.028(-0.048, -0.009)

0.010

GLR

0.573(0.560,0.586)

-0.090(-0.104, -0.075)

 < 0.001

-0.316(-0.365, -0.269)

 < 0.001

-0.119(-0.139, -0.099)

 < 0.001

PLR

0.570(0.556,0.583)

-0.093(-0.108, -0.079)

 < 0.001

-0.320(-0.361, -0.264)

 < 0.001

-0.111(-0.133, -0.087)

 < 0.001

PNI

0.624(0.611,0.637)

-0.039(-0.050, -0.028)

 < 0.001

-0.229(-0.291, -0.166)

 < 0.001

-0.066(-0.089, -0.047)

 < 0.001

GNRI

0.623(0.610,0.636)

-0.040(-0.050, -0.030)

 < 0.001

-0.207(-0.270, -0.150)

 < 0.001

-0.060(-0.079, -0.040)

 < 0.001

AGR

0.606(0.593,0.619)

-0.057(-0.071, -0.044)

 < 0.001

-0.221(-0.278, -0.176)

 < 0.001

-0.062(-0.086, -0.039)

 < 0.001

CONUT

0.599(0.586,0.612)

-0.064(-0.076, -0.051)

 < 0.001

-0.271(-0.327, -0.223)

 < 0.001

-0.084(-0.104, -0.068)

 < 0.001

  1. cNRI Continuous net reclassification improvement, IDI Integrated discrimination improvement