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Table 2 The classes and specific chemotherapeutic agents used by cancer patients, Uganda

From: Frequency, severity, and factors associated with clinically significant drug-drug interactions among patients with cancer attending Mbarara Regional Referral Hospital Cancer Unit, Uganda

Classes of chemotherapeutic agents

(Frequency, Percentage)

Specific chemotherapeutic agents

(Frequency, Percentage)

Plant alkaloids and other natural products (143, 47.7%)

Vincristine (57, 19%), Docetaxel (44, 14.7%), Paclitaxel (29, 9.7%), Etoposide (13, 4.3%), Irinotecan (2, 0.7%), Vinblastine (2, 0.7%)

Antimetabolites (103, 34.3%)

Capecitabine (32, 10.7%), Fluorouracil (30, 10%), Methotrexate (30, 10%), Gemcitabine (14, 4.7%), Mercaptopurine (10, 3.3%), Cytarabine (10, 3.3%)

Platinum analogues (66, 22%)

Oxaliplatin (32, 10.7%), Cisplatin (25, 8.3%), Carboplatin (9, 3%)

Cytotoxic antimetabolites (62, 20.7%)

Doxorubicin (44, 14.7%), Bleomycin (10, 3.3%), Epirubicin (7, 2.3%), Dactinomycin (7, 2.3%), Daunorubicin (5, 1.7%)

Alkylating agents (58, 19.3%)

Cyclophosphamide (41, 13.7%), Dacarbazine (9, 3%), Ifosfamide (3, 1%), Melphalan (3, 1%), Chlorambucil (2, 0.7%)

Endocrine therapy (53, 17.7%)

Goserelin (35, 11.7%), Bicalutamide (27, 9%), Tamoxifen (6, 2%), Abiraterone (4, 1.3%), Anastrozole (2, 0.7%)

Protein kinase inhibitors (23, 7.7%)

Imatinib (15, 5%), Erlotinib (6, 2%), Nintedanib (2, 0.7%), Sorafenib (1, 0.3%), Bortezomib (1, 0.3%)

Miscellaneous (14, 4.7%)

Thalidomide (6, 2%), Asparaginase (5, 1.7%), Arsenic-trioxide (2, 0.7%), Rituximab (1, 0.3%), Tamsulosin (1, 0.3%)