Fig. 5
From: Transcription factor c-Jun modulates GLUT1 in glycolysis and breast cancer metastasis
Relation of GLUT1 and JUN and their expression in human breast cancer tissues. a and b The mRNA expression and protein phosphorylation at T239S243 of JUN (UALCAN database). c Tumor stage, p = 0.000634 (GEPIA database). d Overall survival, p < 0.001 (GENT2 database). e Relationship between methylation (CpG island at 5’UTR and 1stExon of JUN) and overall survival (MethSurv web tool). f The correlation of JUN and GLUT1, p = 0.0001, r = − 0.13 (bc-GenExMiner web tool). g and h The mRNA level of GLUT1 and JUN in 38 paired human breast cancer samples by qRT-PCR. *p < 0.05, **p < 0.01, ***p < 0.001 ****p < 0.0001. Error bars, mean ± SD. i IHC results of GLUT1. Scale bars, 50 μm