Table 2 EGFR/TP53 co-mutation patients treatment outcomes
T group n (%) | TC group n (%) | P | |
|---|---|---|---|
Response | |||
CR | 0 | 0 | |
PR | 21(34.4) | 19(55.9) | 0.042 |
SD | 35(57.4) | 14(41.2) | 0.130 |
PD | 5(8.2) | 1(2.9) | 0.313 |
ORR | 21(34.4) | 19(55.9) | 0.042 |
DCR | 56(91.8) | 33(97.1) | 0.313 |
TTP | |||
6 months progression free | 52(85.2) | 31(91.2) | 0.404 |
12 months progression free | 22(36.1) | 23(67.6) | 0.003 |
18 months progression free | 8(13.1) | 12(35.3) | 0.011 |
OS | |||
1-year OS | 54(88.5) | 32(94.1) | 0.372 |
2-year OS | 32(52.5) | 22(64.7) | 0.248 |