Skip to main content

Table 2 Univariate analysis of DFS and OS in esophageal squamous cell carcinoma

From: Patterns and prognostic predictive value of perineural invasion in esophageal squamous cell carcinoma

Variable

DFS

OS

Median

95%CI

P

Median

95%CI

P

Sex

  

0.037

  

0.027

 Man

28.6

21.8–35.5

 

35.2

27.2–43.3

 

 Woman

42.9

22.3–63.4

 

55.7

21.9–89.6

 

Age

  

0.426

  

0.329

 <65 years

33.4

25.1–41.7

 

42.3

30.5–54.0

 

  ≥ 65 years

26.4

20.5–32.4

 

30.0

20.4–39.4

 

Tumor location

  

0.699

  

0.670

 Upper

27.2

21.0–33.3

 

35.2

19.3–51.2

 

 Middle

35.3

26.7–43.9

 

42.5

30.1–5.9

 

 Lower

27.2

19.5–35.0

 

31.4

10.5–52.2

 

Tumor length

  

0.002

  

0.013

  ≤ 4.0 cm

42.9

32.4–53.3

 

49.1

36.9–61.4

 

 >4.0 cm

26.4

20.7–32.2

 

29.9

19.4–40.4

 

Differentiation

  

0.799

  

0.664

 G1

30.0

19.8–40.2

 

35.0

23.1–47.0

 

 G2

32.0

21.2–42.9

 

41.9

25.8–57.9

 

 G3

35.3

20.0–50.5

 

45.6

25.8–65.4

 

p T stage

  

0.001

   

 T1

85.9

46.2–125.7

 

85.9

NA

0.002

 T2

41.4

33.0–49.8

 

43.9

11.1–76.6

 

 T3

26.8

20.9–32.8

 

32.6

25.2–40.0

 

 T4

14.3

0.0–80.3

 

20.0

0.0–79.9

 

p N stage

  

<0.001

  

<0.001

 N0

59.5

34.4–84.6

 

82.6

58.6–106.6

 

 N1

25.9

18.2–33.7

 

36.7

24.9–48.5

 

 N2

13.5

10.3–16.7

 

17.9

12.8–23.0

 

 N3

8.8

2.0–15.5

 

11.8

9.8–13.7

 

p TNM stage

  

<0.001

  

<0.001

 I stage

71.4

43.5–99.3

 

85.9

NA

 

 II stage

55.7

26.3–85.1

 

66.6

57.4–97.8

 

 III stage

18.8

11.7–25.9

 

45.7

21.5–31.3

 

 IV stage

10.8

4.9–16.6

 

11.9

9.9–14.0

 

Perineural invasion

  

<0.001

  

<0.001

 Present

19.9

13.1–26.7

 

26.4

22.1–30.7

 

 Absent

43.9

26.4–61.3

 

62.5

39.0–85.9