Table 1 Correlation between perineural invasion and clinicopathological characteristics of esophageal squamous cell carcinoma
Variable | Total | Perineural invasion | P value | |
|---|---|---|---|---|
349 | Present(%) | Absent(%) | ||
Sex | 0.432 | |||
Man | 255 | 94(36.9) | 161(63.1) | |
Woman | 94 | 33(35.1) | 61(64.9) | |
Age | 0.496 | |||
<65 years | 287 | 105(36.6) | 182(63.4) | |
≥ 65 years | 62 | 22(35.5) | 40(64.5) | |
Tumor location | ||||
Upper | 29 | 7(24.1) | 22(75.9) | 0.195 |
Middle | 223 | 88(39.5) | 135(60.5) | |
Lower | 97 | 32(33.0) | 65(67.0) | |
Tumor length | 0.314 | |||
≤ 4.0 cm | 175 | 61(34.9) | 114(65.1) | |
>4.0 cm | 174 | 66(37.9) | 108(62.1) | |
Differentiation | 0.150 | |||
G1 | 106 | 46(43.4) | 60(56.6) | |
G2 | 161 | 51(31.7) | 110(68.3) | |
G3 | 82 | 30(36.6) | 52(63.4) | |
p T stage | ||||
T1 | 38 | 7(18.4) | 31(81.6) | 0.010 |
T2 | 70 | 19(27.1) | 51(72.9) | |
T3 | 233 | 97(41.6) | 136(58.4) | |
T4 | 8 | 4(50.0) | 4(50.0) | |
p N stage | <0.001 | |||
N0 | 189 | 50(26.5) | 139(73.5) | |
N1 | 90 | 40(44.4) | 50(55.6) | |
N2 | 58 | 31(53.4) | 27(46.6) | |
N3 | 12 | 6(50.0) | 6(50.0) | |
p TNM stage | <0.001 | |||
I stage | 44 | 8(18.2) | 36(81.8) | |
II stage | 145 | 42(29.0) | 103(71.0) | |
III stage | 147 | 70(47.6) | 77(52.4) | |
IV stage | 13 | 7(53.8) | 6(46.2) | |