Genes | subtypes | Â | Â | Â | Â | Â | Â | Â | Â | Â |
---|---|---|---|---|---|---|---|---|---|---|
 | Basal/Claudin-low Vs. HER2 | Basal/Claudin-low Vs. Luminal A | Basal/Claudin-low Vs. Luminal B | Basal/Claudin-low Vs. Normal | HER2 Vs. Luminal A | HER2 Vs. Luminal B | HER2 Vs. Normal | Luminal A Vs. Luminal B | Luminal A Vs. Normal | Luminal B Vs. Normal |
NOTCH-1 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0239 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
NOTCH-2 |  < 0.0001 | 0.0280 |  < 0.0001 | 0.0290 |  < 0.0001 | 0.8522 | 0.0410 | 0.0410 | 0.2445 | 0.0139 |
NOTCH-3 | 0.2749 | 0.0535 |  < 0.0001 | 0.9757 | 0.0008 |  < 0.0001 | 0.2773 |  < 0.0001 | 0.1330 |  < 0.0001 |
JAG1 |  < 0.0001 | 0.0208 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.5840 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
DLL1 | 0.0008 | 0.7272 |  < 0.0001 |  < 0.0001 | 0.0002 | 0.0003 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
LFNG |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.4220 | 0.0726 | 0.0125 | 0.0897 | 0.0094 | 0.2392 |
ST3GAL6 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0376 | 0.8781 | 0.0260 | 0.0046 | 0.4143 | 0.0116 |
FBXW11 | 0.0163 |  < 0.0001 |  < 0.0001 | 0.1405 |  < 0.0001 |  < 0.0001 | 0.0042 |  < 0.0001 | 0.0094 |  < 0.0001 |
DTX1 | 0.8746 | 0.0003 |  < 0.0001 | 0.3039 | 0.0076 |  < 0.0001 | 0.3279 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
DTX2 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0772 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0013 |  < 0.0001 |
DTX4 | 0.8560 |  < 0.0001 |  < 0.0001 | 0.5745 |  < 0.0001 |  < 0.0001 | 0.5069 | 0.2852 |  < 0.0001 | 0.0009 |
CUL1 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.7459 | 0.0227 | 0.0375 |
ARRB1 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0015 |  < 0.0001 | 0.0176 | 0.7954 | 0.1000 |
SKP1 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0168 |  < 0.0001 |  < 0.0001 |
RBX1 |  < 0.0001 | 0.0794 | 0.0168 |  < 0.0001 |  < 0.0001 | 0.4207 | 0.2319 | 0.0002 |  < 0.0001 | 0.1287 |
KAT2A | 0.9532 |  < 0.0001 |  < 0.0001 | 0.0070 |  < 0.0001 | 0.0001 | 0.0430 | 0.5435 | 0.4026 | 0.2728 |
MAML2 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0005 | 0.4603 | 0.0992 |  < 0.0001 | 0.0011 |  < 0.0001 |  < 0.0001 |
PPARD | 0.3814 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.7865 | 0.1813 | 0.1579 |
TCF7L2 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.1177 | 0.6095 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
PSENEN |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.2374 |  < 0.0001 | 0.3534 |  < 0.0001 | 0.0007 |  < 0.0001 |  < 0.0001 |
PSEN2 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0234 | 0.5739 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0061 |
APH1A | 0.3314 | 0.2413 | 0.0303 |  < 0.0001 | 0.0256 | 0.4093 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
PRKCα |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.9256 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
SAP30 |  < 0.0001 | 0.6201 | 0.0001 |  < 0.0001 |  < 0.0001 | 0.0773 | 0.0030 | 0.0002 |  < 0.0001 | 0.0007 |
HEY1 | 0.0321 |  < 0.0001 | 0.4648 |  < 0.0001 |  < 0.0001 | 0.0816 | 0.0001 |  < 0.0001 | 0.4229 |  < 0.0001 |
HES1 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0354 | 0.0262 | 0.0004 |  < 0.0001 | 0.0325 |  < 0.0001 |
CCND1 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0177 |  < 0.0001 |  < 0.0001 |  < 0.0001 |
WNT2 | 0.8885 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.2228 | 0.0057 | 0.0024 |
WNT5A | 0.2470 |  < 0.0001 | 0.0449 |  < 0.0001 |  < 0.0001 | 0.5831 | 0.0001 |  < 0.0001 | 0.0065 | 0.0005 |
FZD1 |  < 0.0001 | 0.2190 |  < 0.0001 | 0.2373 |  < 0.0001 | 0.0351 |  < 0.0001 |  < 0.0001 | 0.0269 |  < 0.0001 |
FZD5 | 0.0003 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.0028 | 0.0543 | 0.0056 | 0.0383 | 0.7824 |
FZD7 |  < 0.0001 |  < 0.0001 |  < 0.0001 | 0.4576 |  < 0.0001 | 0.0500 |  < 0.0001 |  < 0.0001 |  < 0.0001 |  < 0.0001 |