Table 3 Baseline clinical and biological characteristics of matched patients
Characteristics | CD56 positive | CD56 negative | ||
|---|---|---|---|---|
ASCT | non-ASCT | ASCT | non-ASCT | |
n = 93 | n = 93 | n = 40 | n = 40 | |
n (%) | n (%) | n (%) | n (%) | |
Median age (range) [years] | 56 (36–65) | 57 (38–65) | 57 (38–65) | 57 (35–65) |
ISS stage | ||||
I | 16 (17.2) | 13 (14.0) | 11 (27.5) | 9 (22.5) |
II | 34 (36.6) | 39 (41.9) | 12 (30.0) | 12 (30.0) |
III | 43 (46.2) | 41 (44.1) | 17 (42.5) | 19 (47.5) |
Hemoglobin | ||||
< 100 g/L | 57 (61.3) | 62 (66.7) | 20 (50.0) | 24 (60.0) |
≥ 100 g/L | 36 (38.7) | 31 (33.3) | 20 (50.0) | 16 (40.0) |
Serum creatinine | ||||
≤ 2 mg/dL | 80 (86.0) | 80 (86.0) | 35 (87.5) | 36 (90.0) |
> 2 mg/dL | 13 (14.0) | 13 (14.0) | 5 (12.5) | 4 (10.0) |
Corrected serum calcium | ||||
≤ 2.75 mmol/L | 82 (88.2) | 80 (86.0) | 37 (92.5) | 36 (90.0) |
> 2.75 mmol/L | 11 (11.8) | 13 (14.0) | 3 (7.5) | 4 (10.0) |
Lactate dehydrogenase | ||||
≤ 250 U/L | 83 (89.2) | 81 (87.1) | 34 (85.0) | 33 (82.5) |
> 250 U/L | 10 (10.8) | 12 (12.9) | 6 (15.0) | 7 (17.5) |
Cytogenetic abnormalities by FISH | ||||
del(17p13) | ||||
abnormality | 10 (10.8) | 12 (12.9) | 2 (5.0) | 1 (2.5) |
non-abnormality | 83 (89.2) | 81 (87.1) | 38 (95.0) | 39 (97.5) |
t(14; 16) | ||||
abnormality | 0 (0.0) | 0 (0.0) | 3 (7.5) | 5 (12.5) |
non-abnormality | 93 (100.0) | 93 (100.0) | 37 (92.5) | 35 (87.5) |
t(4; 14) | ||||
abnormality | 26 (28.0) | 25 (26.9) | 0 (0.0) | 0 (0.0) |
non-abnormality | 67 (72.0) | 68 (73.1) | 40 (100.0) | 40 (100.0) |