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Fig. 1 | BMC Cancer

Fig. 1

From: ATBF1 is a potential diagnostic marker of histological grade and functions via WNT5A in breast cancer

Fig. 1

The expression of ATBF1 was reduced in breast cancer tissues (BCTs) compared with that in adjacent noncancerous tissues (ANCTs) at both mRNA and protein levels. A The mRNA levels of ATBF1 in paired ANCTs and BCTs (n = 31) as determined by real-time qPCR. B Molecular structure of ATBF1 and the respective recognition site of three anti-ATBF1 antibodies.BC029653 recognizes the amino acids from 517 to 787; D1-120 recognizes the amino acids from 2107 to 2147; 3B1 recognizes the amino acids from 2811 to 2910. C The protein levels of ATBF1 in all cases (43 ANCTs and 80 BCTs as a pool respectively). D The protein levels of ATBF1 in paired ANCTs and BCTs (n = 43). The expression of ATBF1 protein were determined by IHC staining. Weight index (WI) was used to quantify the protein levels of ATBF1 by multiplying staining intensity by the percentage of positive cells, as previously reported [11]. P-value was calculated by student’s t test under paired (A &D) or unpaired (C)

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