Table 1 Patient-reported outcome assessments

EQ-5D-5 L [ 20 ]

 Visual analogue scale

• Records self-rated health on a vertical VAS

• “We would like to know how good or bad your health is TODAY”

• Ranges from 0 (worst imaginable state of health) to 100 (best imaginable state of health)

EORTC QLQ-C30 [ 21 ]

 Physical function

• Five questions evaluating strength, endurance, and daily physical functioning

• Four-point rating scale ranging from “1-not at all” to “4-very much”

• Responses were rolled up to a score ranging from 0 to 100 in which a larger value is better, per the EORTC manual [23]

 Role function

• Two questions evaluating limitations during everyday activities

• Four-point rating scale ranging from “1-not at all” to “4-very much”

• Responses were rolled up to a score ranging from 0 to 100 in which a larger value is better, per the EORTC manual [23]

 Overall health (question C29) ^a

• One question asking patients to rate their overall health during the past week on a scale of 1 (very poor) to 7 (excellent)

 Overall quality of life (question C30) ^a

• One question asking patients to rate their overall quality of life during the past week on a scale of 1 (very poor) to 7 (excellent)