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Table 2 Univariable analysis and multivariable logistic regression of clinicopathological variables associated with PPOI

From: Nomogram for prediction of prolonged postoperative ileus after colorectal resection

 

PPOI, No

P value

Multivariate Analysis

Absence (n = 128)

Presence (n = 1126)

OR(95% CI)

P value

Gender

  

0.003

1.933(1.219–3.064)

0.005

 Male

103(80.5%)

761(67.6%)

   

 Female

25(19.5%)

365(32.4%)

   

Age(years)

  

0.001

1.823(1.240–2.679)

0.002

  ≤ 65

46(35.9%)

579(51.4%)

   

  > 65

82(64.1%)

547(48.6%)

   

BMI (kg/m2, mean ± SD)

23.7 ± 2.4

23.3 ± 2.3

0.133

  

Smoking habit

  

0.184

  

 Yes

38(29.7%)

274(24.3%)

   

 No

90(70.3%)

852(75.7%)

   

Alcohol use

  

0.282

  

 Yes

60(46.9%)

472(41.9%)

   

 No

68(53.1%)

654(58.1%)

   

Diabetes Mellitus

  

0.102

  

 Yes

37(28.9%)

253(22.5%)

   

 No

91(71.1%)

873(77.5%)

   

Hypertension

  

0.224

  

 Yes

42(32.8%)

312(27.7%)

   

 No

86(67.2%)

814(72.3%)

   

Hyperlipidemia

  

0.428

  

 Yes

45(35.2%)

357(31.7%)

   

 No

83(64.8%)

769(68.3%)

   

Respiratory comorbidity

  

0.529

  

 Yes

28(21.9%)

220(19.5%)

   

 No

100(78.1%)

906(80.5%)

   

Cardiac comorbidity

  

0.151

  

 Yes

31(24.2%)

213(18.9%)

   

 No

97(75.8%)

913(81.1%)

   

Peripheral vascular disease

  

0.348

  

 Yes

23(18.0%)

167(14.8%)

   

 No

105(82.0%)

959(85.2%)

   

Previous abdominal surgery

  

0.176

  

 Yes

23(18.0%)

153(13.6%)

   

 No

105(82.0%)

973(86.4%)

   

Preoperative anemia

  

0.291

  

 Yes

48(37.5%)

370(32.9%)

   

 No

80(62.5%)

756(67.1%)

   

Preoperative hypoalbuminemia

  

0.361

  

 Yes

24(18.8%)

176(15.6%)

   

 No

104(81.2%)

950(84.4%)

   

Preoperative WBC count( ×103/μL, mean ± SD)

7.0 ± 1.4

6.8 ± 1.7

0.207

  

Neoadjuvant treatment

  

0.210

  

 Yes

30(23.4%)

212(18.8%)

   

 No

98(76.6%)

914(81.2%)

   

ASA-classification

  

0.376

  

 ASA I

72(56.3%)

704(62.5%)

   

 ASA II

39(30.5%)

299(26.6%)

   

 ASA III, IV

17(13.3%)

123(10.9%)

   

Surgical approach

  

0.000

2.436(1.519–3.907)

0.000

 Minimally invasive surgery

100(78.1%)

1015(90.1%)

   

 Open/conversion

28(21.9%)

111(9.9%)

   

Surgical procedure

  

0.099

  

 Right colectomy

38(29.7%)

294(26.1%)

   

 Transverse colectomy

8(6.3%)

70(6.2%)

   

 Left colectomy

22(17.2%)

308(27.4%)

   

 Rectal resectiona

60(46.9%)

454(40.3%)

   

Diverting ileostomy

  

0.432

  

 Yes

21(16.4%)

156(13.9%)

   

 No

107(83.6%)

970(86.1%)

   

Operation duration(min)

  

0.047

1.415(0.963–2.078)

0.077

  ≤ 180

48(37.5%)

526(46.7%)

   

  > 180

80(62.5%)

600(53.3%)

   

Intraoperative Blood loss (mL), (median [IQR])

200(100,250)

180(90,230)

0.063

  

Bowel resection length (cm), (median [IQR])

20(18,22)

19(17,21)

0.366

  

Anastomosis technique

  

0.446

  

 Side-to-end

29(22.7%)

290(25.8%)

   

 End-to-end

99(77.3%)

836(74.2%)

   

Anastomosis approach

  

0.078

  

 Intracorporeal anastomosis

25(19.5%)

301(26.7%)

   

 extracorporeal anastomosis

103(80.5%)

825(73.3%)

   

Intraoperative fluid overload

  

0.001

1.844(1.264–2.690)

0.001

 Yes

75

485

   

 No

53

641

   

Perioperative transfusion

  

0.381

  

 Yes

14(10.9%)

97(8.6%)

   

 No

114(89.1%)

1029(91.4%)

   

Differentiation

  

0.820

  

 Well

7(5.5%)

58(5.2%)

   

 Moderate

109(85.2%)

942(83.7%)

   

 Poor

12(9.4%)

126(11.2%)

   

Specimen extraction approaches

  

0.071

  

 Natural orifice specimen extraction

6(4.7%)

107(9.5%)

   

 Conventional extraction

122(95.3%)

1019(90.5%)

   

TNM stage

  

0.649

  

 I

18(14.1%)

195(17.3%)

   

 II

67(52.3%)

568(50.4%)

   

 III

43(33.6%)

363(32.2%)