Fig. 6

The Effect of DRD3 on tumor growth in vivo. (A, B) Knock-down of DRD3 could promote tumor growth in vivo, and SCH772984 could also abolished this effect in vivo. (C) The cAMP level of three groups of tumors. (D, E) PD128907 suppressed tumor growth in vivo, and U99194 promoted tumor growth in vivo. (F) Model illustrating possible mechanisms by which the loss of DRD3 contributes to HCC progression. * P < 0.05, ** P < 0.01, *** P < 0.001