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Fig. 2 | BMC Cancer

Fig. 2

From: TG2 as a novel breast cancer prognostic marker promotes cell proliferation and glycolysis by activating the MEK/ERK/LDH pathway

Fig. 2

TG2 is necessary for breast cancer proliferation in vivo and in vitro. A The mRNA expression of TG2 was detected in breast cancer cell lines. B and C The TG2 knockdown and overexpression cell line was established in SK-BR-3 and BT-474 cells, respectively. D and E The proliferation ability was measured by CCK-8 assay in TG2 overexpression (BT-474) and knockdown (SK-BR-3) cell line. F-H The xenograft model was established in nude female mice by injection SK-BR-3 cells (scramble control  [SC] and knockdown [KD]), orthotopically. (* p<0.05, ** p<0.01)

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BMC Cancer

ISSN: 1471-2407

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