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Table 5 Jointed effects of rs1366600 and smoking status on ESCC risk validated by the logistic regression model

From: Genetic variant in miR-17-92 cluster binding sites is associated with esophageal squamous cell carcinoma risk in Chinese population

Smoking status

rs1366600

Controls

Cases

ORs (95% CI)a

Pa

A/G

n (%)

n (%)

With smoking

AA

261 (51.0)

192 (39.4)

1.000

 

AG + GG

118 (23.0)

70 (14.3)

0.739 (0.467–1.168)

0.195

Without smoking

AA

86 (16.8)

161 (33.0)

0.350 (0.237–0.516)

< 0.001

AG + GG

47 (9.2)

65 (13.3)

0.320 (0.195–0.527)

< 0.001

  1. aORs (95% CI) and P-values were obtained by the logistic regression analysis after adjustment for age, gender and family history of cancers, ESCC Esophageal squamous cell carcinoma, OR Odds ratio, CI Confidence interval