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Table 3 Associations of the selected SNPs with the risk of ESCC in four genetic models

From: Genetic variant in miR-17-92 cluster binding sites is associated with esophageal squamous cell carcinoma risk in Chinese population

 

Additive model

Dominant model

Recessive model

Codominant modelb

      

het

hom

SNPs

OR (95%CI)a

Pa

OR (95%CI)a

Pa

OR (95%CI)a

Pa

OR (95%CI)a

Pa

OR (95%CI)a

Pa

rs12594531

0.930 (0.773–1.118)

0.438

0.909 (0.692–1.193)

0.491

0.909 (0.650–1.269)

0.574

0.924 (0.694–1.231)

0.591

0.866 (0.594–1.263)

0.455

rs1366600

0.813 (0.638–1.036)

0.094

0.785 (0.594–1.037)

0.088

0.788 (0.367–1.692)

0.541

0.790 (0.592–1.055)

0.110

0.737 (0.342–1.591)

0.437

rs1804506

0.817 (0.681–0.981)

0.030

0.765 (0.578–1.012)

0.060

0.767 (0.559–1.054)

0.102

0.807 (0.600–1.085)

0.155

0.670 (0.463–0.968)

0.033

rs3741779

0.896 (0.736–1.092)

0.278

0.944 (0.732–1.218)

0.660

0.680 (0.432–1.069)

0.095

1.008 (0.772–1.316)

0.951

0.683 (0.426–1.093)

0.112

rs3763763

1.053 (0.860–1.288)

0.618

1.056 (0.818–1.363)

0.677

1.104 (0.682–1.786)

0.687

1.043 (0.798–1.363)

0.757

1.124 (0.685–1.845)

0.643

  1. aadjusted for age, gender, smoking status and family history of cancers in logistic regression model
  2. bhet Heterozygote vs major homozygote, hom Minor homozygote vs major homozygote, CI Confidence interval, OR Odds ratio, SNP Single nucleotide polymorphism