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Table 2 Detailed information of the selected SNPs

From: Genetic variant in miR-17-92 cluster binding sites is associated with esophageal squamous cell carcinoma risk in Chinese population

SNPs

Genes

Associated miRNAs

Location (GRCh 38)

Allelesa

Casesb (n = 488)

Controlsb (n = 512)

MAFc

PHWEd

rs12594531

THSD4

miR-18a-5p

Chr15: 71782166

C/A

166/240/82

158/260/94

0.438

0.473

rs1366600

INSR

miR-17-5p/miR-20a-5p

Chr19: 7112870

A/G

353/122/13

347/149/16

0.177

0.999

rs1804506

TGFBR3

miR-19a-3p/miR-19b-3p

Chr1: 91682456

C/T

158/242/88

135/260/117

0.482

0.702

rs3741779

SSH1

miR-19a-3p/miR-19b-3p

Chr12: 108785032

C/T

232/221/35

238/219/55

0.321

0.663

rs3763763

TACC2

miR-92a-3p

Chr10: 122254089

C/A

252/196/40

276/200/36

0.266

0.977

rs8323

CX3CL1

miR-17-5p/miR-20a-5p

Chr16: 57384770

C/T

240/211/37

226/245/41

0.319

0.023

  1. aMajor/minor alleles; bNumbers of major homozygote/heterozygote/minor homozygote; cMinor allele frequency (MAF) in our controls; dHardy-Weinberg equilibrium (HWE) in our controls
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BMC Cancer

ISSN: 1471-2407

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