Fig. 3

(a) UMAP clustering of JPAs based on the compartment scores along chromosome 7 (50 kb bins) shows two clusters separating JPAs and normal adult astrocytes from other tumor types and normal controls for other brain regions. b Correlation matrix showing hierarchical clustering by compartment score along chromosome 7 (50 kb bins) shows two clusters separating JPAs and normal astrocytes from other tumor types and normal controls for other brain regions. c Compartment score over KIAA1549 and BRAF showing that both genes are in open chromatin regions in JPAs (regardless of fusion) but not in normal adult astrocytes