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Fig. 2 | BMC Cancer

Fig. 2

From: Clinicopathological findings, prognosis, and Epstein–Barr virus infection in rheumatoid arthritis patients with other iatrogenic immunodeficiency-associated T- and NK-cell lymphoproliferative disorders

Fig. 2

A: Diffuse invasion by large, atypical lymphocytes in nodal CD4+ TFH+ PTCL (Case No. 1). B: Diffuse infiltrates of small, atypical lymphocytes and plasma cells and moderate vascular reactions were found in nodal CD4+ TFH+ T-LPDs (Case No. 6). C: Diffuse infiltrate of large, atypical lymphocytes with round nuclei and distinct nucleoli in nodal EBER+ CD4+ PTCL-NOS (Case No. 8). Intrahepatic invasion by large, atypical lymphocytes with lobulated nuclei were observed (D), along with bone marrow invasion by medium-sized and large, atypical lymphocytes and two phagocytic macrophages (E) in systemic EBV+ CD8+ TCL (Case Nos. 13 and 14). F: Diffuse monotonous infiltrate of small lymphocytes with mild atypia in nodal CD8+ PTCL-NOS (Case No. 17). HE staining, × 400

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BMC Cancer

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