Table 3 Patients’ clinicopathological characteristics according to IDO expression
Variables | IDO (−) (n = 63) | IDO (+) (n = 27) | p-value |
|---|---|---|---|
< Patient’s factor > | |||
 Age (years) | 66.3 ± 10.1 | 65.03 ± 11.1 | 0.62 |
 Sex (men/women) | 45/18 | 18 /9 | 0.65 |
< Pre-CRT factor > | |||
 Stage (I,II/III) | 21/42 | 12/15 | 0.31 |
 Main tumor location (Ra/Rb,P) | 10/53 | 2/25 | 0.26 |
< Treatment factor > | |||
 Drug (S-1/UFT/5-FU) | 54/9/0 | 19/7/1 | 0.11 |
 Surgical procedure (LAR/ISR/APR/Local/TPE) | 27/6/28/2/0 | 13/4/9/0/1 | 0.29 |
< Post-CRT factor > | |||
 Tumor differentiation (diff./undiff.) | 56/7 | 27/0 | 0.02 |
 fStage (I, II/III) | 39/24 | 20/7 | 0.26 |
 T (1,2/3,4) | 24/39 | 15/12 | 0.57 |
 Lymph node metastasis (−/+) | 42/21 | 20/7 | 0.48 |
 Venous invasion (−/+) | 35/28 | 10/17 | 0.11 |
 Lymphatic invasion (−/+) | 43/20 | 22/5 | 0.19 |
 PD-L1 expression (−/+) | 37/26 | 9/18 | 0.03 |
 Pathological response (Non-responder /Responder) | 39/24 | 19/8 | 0.44 |