Table 1 Clinical features of LS-SCLC patients according to LIPI status
From: Prognostic ability of lung immune prognostic index in limited-stage small cell lung cancer
Variables | Un-matched (N = 497) | After PSM (N = 398) | After IPTW (N = 993) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Low Risk (n = 250) | High Risk (n = 247) | P value | Low Risk (n = 199) | High Risk (n = 199) | P value | Low Risk (n = 497.3) | High Risk (n = 495.7) | P value | |
age60 | 0.813 | 0.688 | 0.882 | ||||||
< 60 | 116(46.4%) | 112(45.3%) | 95(47.7%) | 91(45.7%) | 229.0 (46.0%) | 225.9 (45.6%) | |||
> =60 | 134(53.6%) | 135(54.7%) | 104(52.3%) | 108(54.3%) | 268.4 (54.0%) | 269.8 (54.4%) | |||
gender | 0.399 | 0.370 | 0.564 | ||||||
Female | 52(20.8%) | 44(17.8%) | 41(20.6%) | 34(17.1%) | 99.4 (20.0%) | 91.9 (18.5%) | |||
Male | 198(79.2%) | 203(82.2%) | 158(79.4%) | 165(82.9%) | 398.0 (80.0%) | 403.8 (81.5%) | |||
smoke | 0.397 | 0.728 | 0.483 | ||||||
No | 68(27.2%) | 59(23.9%) | 51(25.6%) | 48(24.1%) | 130.2 (26.2%) | 120.2 (24.2%) | |||
Yes | 182(72.8%) | 188(76.1%) | 148(74.4%) | 151(75.9%) | 367.1 (73.8%) | 375.5 (75.8%) | |||
KPS | 0.034 | 1.000 | 0.860 | ||||||
0–1 | 218(87.2%) | 198(80.2%) | 170(85.4%) | 170(85.4%) | 414.8 (83.4%) | 411.3 (83.0%) | |||
2 | 32(12.8%) | 49(19.8%) | 29(14.6%) | 29(14.6%) | 82.6 (16.6%) | 84.4 (17.0%) | |||
AJCC TNM 8th | 0.001 | 1.000 | 0.887 | ||||||
I-II | 36(14.4%) | 14(5.7%) | 12(6.0%) | 12(6.0%) | 49.9 (10.0%) | 48.4 (9.8%) | |||
III | 214(85.6%) | 233(94.3%) | 187(94.0%) | 187(94.0%) | 447.4 (90.0%) | 447.3 (90.2%) | |||
cycles | 0.020 | 1.000 | 0.947 | ||||||
< 4 | 66(26.4%) | 89(36.0%) | 59(29.7%) | 59(29.7%) | 153.8 (30.9%) | 154.3 (31.1%) | |||
> =4 | 184(73.6%) | 158(64.0%) | 140(70.3%) | 140(70.3%) | 343.5 (69.1%) | 341.5 (68.9%) | |||
RT | 0.166 | 0.688 | 0.737 | ||||||
No | 112(44.8%) | 126(51.0%) | 94(47.2%) | 90(45.2%) | 239.2 (48.1%) | 233.1 (47.0%) | |||
Yes | 138(55.2%) | 121(49.0%) | 105(52.8%) | 109(54.8%) | 258.2 (51.9%) | 262.6 (53.0%) | |||
PCI | 0.005 | 1.000 | 0.954 | ||||||
No | 208(83.2%) | 226(91.5%) | 183(92.0%) | 183(92.0%) | 434.3 (87.3%) | 433.5 (87.4%) | |||
Yes | 42(16.8%) | 21(8.5%) | 16(8.0%) | 16(8.0%) | 63.0 (12.7%) | 62.2 (12.6%) | |||
Treatment | 0.303 | 0.897 | 0.905 | ||||||
early RT | 64(25.6%) | 51(20.7%) | 46(23.1%) | 46(23.1%) | 113.5 (22.8%) | 118.8 (24.0%) | |||
CT only | 112(44.8%) | 126(51.0%) | 94(47.2%) | 90(45.2%) | 239.2 (48.1%) | 233.1 (47.0%) | |||
late RT | 74(29.6%) | 70(28.3%) | 59(29.7%) | 63(31.7%) | 144.6 (29.1%) | 143.8 (29.0%) | |||