Patient reported outcomes based on EQ-5D-5L questionnaires in head and neck cancer patients: a real-world study

BMC Cancer

Table 5 Corresponding EQ-VAS values for aforementioned subgroups

<65y vs. ≥65y health index values
	Questionnaires (n)	Mean of <65y	SD	p-value^a	Questionnaires (n)	Mean of ≥65y	SD	p-value^a	p-value^b
Baseline	105	60,38	24,01	< 0.0001	117	63,58	23,87	0,155	0,343
RT end	54	54,63	20,71		59	77,80	21,30		0,009
Total	159				176
Male vs. female health index values
	Questionnaires (n)	Mean of male	SD	p-value^a	Questionnaires (n)	Mean of female	SD	p-value^a	p-value^b
Baseline	153	63,34	24,12	0,001	68	59,18	23,43	0,057	0,142
RT end	77	70,78	28,45		36	58,06	21,49		0,655
Total	230				104
Definitive vs. adjvant radiotherapy
	Questionnaires (n)	Mean of definitive	SD	p-value^a	Questionnaires (n)	Mean of adjuvant	SD	p-value^a	p-value^b
Baseline	138	61,26	24,42	0,010	83	63,41	23,19	0,0004	0,598
RT end	64	71,88	27,80		49	60,00	20,46		0,959
Total	202				132
Smoker vs. non-smoker
	Questionnaires (n)	Mean of smoker	SD	p-value^a	Questionnaires (n)	Mean of non-smoker	SD	p-value^a	p-value^b
Baseline	76	63,16	23,34	0,0005	67	65,33	22,21	0,252	0,637
RT end	60	56,83	21,41		42	63,57	19,04		0,187
Total	136				109
Inpatient vs.outpatient
	Questionnaires (n)	Mean of inpatient	SD	p-value^a	Questionnaires (n)	Mean of outpatient	SD	p-value^a	p-value^b
Baseline	106	63,13	23,36	0,0043	115	61,06	24,53	0,0007	0,452
RT end	71	68,10	12,80		42	64,40	20,49		0,048
Total	177				157
Chemotherapy vs.no chemotherapy
	Questionnaires (n)	Mean of chemotherapy	SD	p-value^a	Questionnaires (n)	Mean of no chemotherapy	SD	p-value^a	p-value^b
Baseline	92	66,07	22,12	0,016	117	59,74	24,79	0,031	0,065
RT end	51	72,55	12,7		60	62,83	19,99		0,109
Total	143				177

Abbreviation: ^awithin group, p-value Kruskal-Wallis test; ^bbetween groups p-value: Mann-Whitney U test, FU Follow up, RT Radiotherapy, SD Standard deviation, VAS Visual analog scale

ISSN: 1471-2407