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Table 4 EQ-5D-5L health index in H&N cancer patients at the baseline and end of treatment for the following subgroups: < 65 vs. ≥65 years old, male vs. female, definitive vs. adjuvant radiotherapy approach, smoker vs. non-smoker, inpatients vs. outpatients, concomitant chemotherapy vs. no chemotherapy

From: Patient reported outcomes based on EQ-5D-5L questionnaires in head and neck cancer patients: a real-world study

<65y vs. ≥65y health index values

 

Questionnaires (n)

Mean of <65y

SD

p-valuea

Questionnaires (n)

Mean of ≥65y

SD

p-valuea

p-valueb

Baseline

105

0,823

0,146

0,871

117

0,782

0,229

0,277

0,976

RT end

54

0,830

0,179

 

59

0,837

0,177

 

0,885

Total

159

   

176

    

Male vs. female health index values

 

Questionnaires (n)

Mean of male

SD

p-valuea

Questionnaires (n)

Mean of female

SD

p-valuea

p-valueb

Baseline

153

0,822

0,196

0,541

68

0,765

0,231

0,118

0,034

RT end

77

0,837

0,150

 

36

0,816

0,188

 

0,561

Total

230

   

104

    

Definitive vs. adjvant radiotherapy

 

Questionnaires (n)

Mean of definitive

SD

p-valuea

Questionnaires (n)

Mean of adjuvant

SD

p-valuea

p-valueb

Baseline

138

0,777

0,223

0,092

83

0,849

0,173

0,193

0,023

RT end

64

0,825

0,152

 

49

0,837

0,177

 

0,429

Total

202

   

132

    

Smoker vs. non-smoker

 

Questionnaires (n)

Mean of smoker

SD

p-valuea

Questionnaires (n)

Mean of non-smoker

SD

p-valuea

p-valueb

Baseline

76

0,817

0,177

0,080

67

0,832

0,212

0,806

0,116

RT end

60

0,833

0,162

 

42

0,836

0,169

 

0,779

Total

136

   

109

    

Inpatient vs.outpatient

 

Questionnaires (n)

Mean of inpatient

SD

p-valuea

Questionnaires (n)

Mean of outpatient

SD

p-valuea

p-valueb

Baseline

106

0,812

0,201

0,048

115

0,797

0,216

0,176

0,941

RT end

71

0,806

0,164

 

42

0,870

0,153

 

0,017

Total

177

   

157

    

Chemotherapy vs.no chemotherapy

 

Questionnaires (n)

Mean of chemotherapy

SD

p-valuea

Questionnaires (n)

Mean of no chemotherapy

SD

p-valuea

p-valueb

Baseline

92

0,870

0,134

0,021

117

0,764

0,239

0,031

0,012

RT end

51

0,831

0,144

 

60

0,832

0,179

 

0,624

Total

143

   

177

    
  1. Abbreviation: awithin group, p-value Kruskal-Wallis test; bbetween groups p-value: Mann-Whitney U test, FU Follow up, RT Radiotherapy, SD Standard deviation, VAS Visual analog scale