Table 3 Cox proportional hazards model for lateral neck recurrence
From: Risk stratification of lateral neck recurrence for patients with pN1a papillary thyroid cancer
Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P -value | HR (95% CI) | P -value | |
Male sex | 1.113(0.716–1.731) | 0.634 | ||
Age (yrs) | ||||
< 55 | 1(ref) | |||
≥ 55 | 0.946(0.505–1.775) | 0.864 | ||
Extent | ||||
Lobectomy | 1(ref) | |||
Total thyroidectomy | 1.044(0.656–1.662) | 0.857 | ||
Primary tumor size | ||||
≤ 1 cm | 1(ref) | 1(ref) | ||
1–2 cm | 1.875(1.099–3.197) | 0.021 | 1.598(0.918–2.780) | 0.097 |
> 2 cm | 4.921(2.911–8.317) | 0.000 | 4.225(2.460–7.256) | 0.000 |
Bilaterality | 1.137(0.645–2.007) | 0.657 | ||
Multifocality | 1.547(1.026–2.334) | 0.037 | 1.607(1.055–2.447) | 0.027 |
Hashimoto thyroiditis | 0.814(0.468–1.416) | 0.466 | ||
Extrathyroidal extension | 1.887(1.237–2.880) | 0.003 | 1.637(1.054–2.544) | 0.028 |
Extranodal extension | 1.753(1.023–3.003) | 0.041 | ||
CLNMs > 3 | 4.860(3.228–7.318) | 0.000 | 4.389(2.887–6.672) | 0.000 |
RAI | 2.174(0.950–4.976) | 0.066 | ||