Table 6 The cox analysis of DFS

Age, ≥ 60y

0.957(0.623–1.471)

0.841

0.932(0.575–1.512)

0.932

Sex, male

0.897(0.587–1.370)

0.614

1.001(0.637–1.574)

0.996

Tumor location, right side

0.735(0.467–1.156)

0.183

0.708(0.435–1.151)

0.163

Tumor number, multiple

0.782(0.308–1.987)

0.606

0.589(0.191–1.814)

0.357

Three-step process optimization

0.640(0.403–1.017)

0.059

0.627(0.407–0.967)

0.035

0.640(0.398–1.031)

0.066

0.652(0.408–1.043)

0.074

T stage

0.879

0.845

 T1A

Ref

Ref

 T1B

1.198(0.697–2.060)

0.514

1.169(0.670–2.041)

0.582

 T2

1.242(0.701–2.203)

0.458

1.119(0.593–2.111)

0.729

 T3

1.307(0.501–2.144)

0.922

0.947(0.427–2.100)

0.893

 T4

1.720(0.481–6.146)

0.404

1.932(0.555–6.724)

0.301

Margin, R1

0.535(0.154–1.855)

0.324

3.059(0.868–10.779)

0.082

2.250(0.690–7.341)

0.179

Tumor differentiation

0.059

0.012

0.014

 Well

Ref

Ref

Ref

Ref

 Moderate

0.870(0.533–1.418)

0.575

0.915(0.585–1.431)

0.696

0.844(0.503–1.417)

0.522

0.806(0.493–1.318)

0.390

 Poor

4.009(1.075–14.952)

0.039

3.452(1.009–11.805)

0.048

6.117(1.575–23.763)

0.009

4.793(1.374–16.725)

0.014

Macrovascular invasion

0.973(0.502–1.883)

0.934

0.723(0.339–1.542)

0.401

Microvascular invasion

1.547(0.981–2.440)

0.060

1.472(0.978–2.215)

0.064

1.548(0.955–2.511)

0.076

1.395(0.889–2.189)

0.147

Capsule

0.970(0.527–1.788)

0.923

1.073(0.551–2.090)

0.835

Satellite lesion

0.722(0.345–1.511)

0.387

0.475(0.205–1.103)

0.083

0.520(0.236–1.144)

0.104