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Fig. 5 | BMC Cancer

Fig. 5

From: CSP I-plus modified rEndostatin inhibits hepatocellular carcinoma metastasis via down-regulation of VEGFA and integrinβ1

Fig. 5

The expression of angiogenesis-related factor and metastasis-associated molecule in HCCLM3 cell. A mRNA expression by RT-PCR; The mRNA expression was quantified using the comparative threshold cycle method. mRNA expression of angiogenesis-related factor VEGFA and metastasis-associated molecule MMP2, integrinβ1 and E-cadherin were shown relative to GAPDH. B Protein expression by Western blotting (Full-length blots are presented in Supplementary Figures); C Statistical analysis of the value of angiogenesis-related factor VEGFA and metastasis-associated molecule MMP2, integrinβ1 and E-cadherin /β-actin. The protein bands were quantified using Image J software, protein expression of VEGFA, MMP2, integrinβ1 and E-cadherin were shown relative to β-actin

rES-CSP group vs Blank group; rES-CSP group vs Endostar group; rES-CSP group vs rES-CSP+ heparin sodium group *P < 0.05, **P < 0.01, ***P < 0.001; n = 3.

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