Table 3 Treatment-related adverse events
Adverse events | All grades | (n, %) | Grade3-4 | (n, %) |
|---|---|---|---|---|
Hypertension | 60 | (58.8) | 20 | (19.6) |
Hand-foot syndrome | 49 | (48.0) | 7 | (6.9) |
Stomatitis | 36 | (35.3) | 6 | (5.9) |
Dysgeusia | 17 | (16.7) | - | - |
Oedema | 14 | (13.7) | 0 | (0) |
Nausea / Vomiting | 24 | (23.5) | 0 | (0) |
Hemorrhage | 26 | (25.5) | 0 | (0) |
Constipation | 16 | (15.7) | 0 | (0) |
Diarrhea | 29 | (28.4) | 3 | (2.9) |
Fatigue | 46 | (45.1) | 7 | (6.9) |
Hypothyroidism | 26 | (25.5) | 5 | (4.9) |
Leukopenia | 55 | (53.9) | 10 | (9.8) |
Thrombocytopenia | 79 | (77.5) | 17 | (16.7) |
Anemia | 70 | (68.6) | 5 | (4.9) |
Elevation of AST | 63 | (61.8) | 8 | (7.8) |
Elevation of serum creatinine | 53 | (52.0) | 5 | (4.9) |
Elevation of ALP | 51 | (51.5) | 1 | (1.0) |