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Table 3 Multivariate analysis of OS and RFS

From: Impact of posttransplant cyclophosphamide on the outcome of patients undergoing unrelated single-unit umbilical cord blood transplantation for pediatric acute leukemia

Variables

HR for OS (95%CI)

p

HR for RFS (95%CI)

p

HLA matching

 10/10 and 9/10

1

0.071

1

0.417

 8/10 and 7/10

7.286(0.842, 63.044)

 

2.706(0.244, 29.967)

 

PTCY

 No

1

0.153

1

0.192

 Yes

4.342(0.581, 32.473)

 

4.178(0.488, 35.801)

 

Remission

 CR1

1

0.360

1

0.002

 CR2

1.986(0.457, 8.624)

 

21.042(3.158, 140.210)

 
  1. HR hazard ratio, 95% CI 95% confidence interval, CR1 first complete remission, CR2 second complete remission, HLA human lymphocyte antigen, PTCY posttransplant cyclophosphamide, GvHD graft-versus-host-disease, OS overall survival, RFS relapse-free survival