Favorable locoregional control in clinically node-negative hormone-receptor positive breast cancer with low 21-gene recurrence scores: a single-institution study with 10-year follow-up

Table 3 Clinicopathological characteristics of patients with locoregional recurrence

Characteristics	Patient 1	Patient 2	Patient 3
Locoregional recurrence type	Breast recurrence	Supraclavicular LN metastasis	Axillary LN metastasis
Family history	No	No	No
Age	50	52	29
Surgery type	BCS&SLNB	BCS&SLNB	Mastectomy&SLNB
Surgical margin distance	10 mm	10 mm	4 mm
Tumor size/ pTNM	1.1 cm/ pT1N0	3 cm/ pT2N0	2 cm/ pT1N0
Histopathology	IDC	IDC	IDC
Histological/ Nuclear Grade	intermediate/intermediate	intermediate/intermediate	intermediate/intermediate
LVI	No	No	No
Multifocality/ EIC	No/No	No/No	No/Yes
ER rate /PR rate	100%/100%	95%/30%	95%/70%
Ki-67 score	10%	11%	18%
21-gene RS	21	17	17
Adjuvant Radiotherapy	Yes	Yes	Yes
Adjuvant Chemotherapy	No	No	No
Type of endocrine therapy	Tamoxifen/leuprolide acetate	letrozole	Tamoxifen/leuprolide acetate
LR time after surgery	98 months	107 months	105 months

RS Recurrence score, LR Locoregional recurrence, LN Lymph node, BCS Breast conserving surgery, SLNB Sentinel lymph node biopsy, IDC Invasive ductal cancer, EIC Extensive intraductal component

ISSN: 1471-2407