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Table 8 Analysis of T cell subsets, IgM, L%, NLR, CRP and D-Dimer in squamous cell carcinoma (SCC) patients

From: Broad-spectrum antibiotics associated gut microbiome disturbance impairs T cell immunity and promotes lung cancer metastasis: a retrospective study

Characteristic (SCC)

Non-ATB (n = 45)

ATB(n = 38)

P value

CD3+ (%)

69.78 ± 9.10

62.61 ± 9.74

0.001

CD4+ (%)

42.81 ± 10.93

33.47 ± 10.33

< 0.001

CD8+ (%)

25.03 ± 10.51

20.90 ± 5.02

0.030

CD4/CD8

1.82 (1.18,2.81)

1.62 (1.18,2.32)

0.315

CD16 + 56+ (%)

15.76 ± 8.10

22.25 ± 10.21

0.002

CD19+ (%)

8.10 (3.98,12.25)

8.30 (6.16,11.49)

0.742

IgM (g/L)

0.91 (0.69,1.45)

0.77 (0.55,1.00)

0.009

L%

18.18 ± 8.95

14.29 ± 6.97

0.032

NLR

4.33 (2.72,6.65)

5.67 (3.59,8.92)

0.040

CRP (mg/L)

23.26 (5.40,70.07)

76.97 (26.06,117.10)

0.001

D-Dimer (mg/L)

0.79 (0.41,1.42)

2.37 (0.64,5.21)

0.003

  1. L% Percentage of lymphocytes, NLR Neutrophil-lymphocyte ratio, CRP C-reactive protein, IgM Immunoglobulin M