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Table 13 Influence of infection on the baseline immune function indexes in lung cancer patients

From: Broad-spectrum antibiotics associated gut microbiome disturbance impairs T cell immunity and promotes lung cancer metastasis: a retrospective study

Characteristic

Non infection group(n = 70)

Infection group (n = 75)

P value

CD3+ (%)

63.40 (54.99,71.20)

66.20 (55.70,70.90)

0.773

CD4+ (%)

35.76 ± 10.57

33.91 ± 11.34

0.312

CD8+ (%)

20.33 (15.30,24.90)

20.30 (15.27,23.66)

0.818

CD4/CD8

1.78 (1.33,2.34)

1.65 (1.18,2.24)

0.437

CD16 + 56+ (%)

17.40 (11.40,26.14)

18.00 (14.70,24.58)

0.495

CD19+ (%)

9.50 (6.18,14.30)

9.56 (5.76,16.50)

0.880

IgM (g/L)

0.83 (0.56,1.08)

0.84 (0.55,1.13)

0.797

L%

15.70 (9.48,22.78)

11.50 (7.00,18.00)

0.019

NLR

4.74 (2.85,8.81)

6.73 (3.92,11.91)

0.017

CRP (mg/L)

17.11 (6.98,63.95)

58.69 (9.25,111.49)

0.025

D-Dimer (mg/L)

3.01 (0.94,5.95)

1.89 (0.88,4.64)

0.183

  1. L% Percentage of lymphocytes, NLR Neutrophil-lymphocyte ratio, CRP C-reactive protein, IgM Immunoglobulin M