Table 1 Clinical characteristics of elderly Korean women with breast cancer
Group | ||||
|---|---|---|---|---|
Variable | Total no. of analyzed patients (%) | Old-onset breast cancer (≥70) | Non old-onset breast cancer (40 ~ 69) | p value |
(N = 102,379) | (N = 6104) | (n = 96,275) | ||
Age, years | 50 (40–108) | 73 (70–108) | 50 (40–69) | <.0011 |
52.46 ± 9.09 | 74.21 ± 4.02 | 51.08 ± 7.41 | ||
Age at menarche, years | ||||
20,574 (20.1) | <.0012 | |||
< 13 | 542 | 21 (0.9) | 521 (2.8) | |
13–16 | 13,410 | 1218 (55.0) | 12,192 (66.4) | |
≥ 17 | 6622 | 975 (44.0) | 5647 (30.8) | |
Missing | 81,805 | 3890 | 77,915 | |
Age at menopause onset, years | ||||
20,574 (20.1) | <.0012 | |||
< 45 | 2277 | 229 (10.3) | 2048 (11.2) | |
45–54 | 16,084 | 1622 (73.3) | 14,462 (78.8) | |
≥ 55 | 2213 | 363 (16.4) | 1850 (10.1) | |
Missing | 81,805 | 3890 | 77,915 | |
Age at first delivery, years | ||||
20,574 (20.1) | <.0012 | |||
< 23 | 4354 | 967 (43.7) | 3387 (18.4) | |
≥ 23 | 16,220 | 1247 (56.3) | 14,973 (81.6) | |
Missing | 81,805 | 3890 | 77,915 | |
Parity | 64,939 (63.4) | .9112 | ||
64,939 (63.4) | <.0012 | |||
0 | 1967 | 116 (3.1) | 1851 (3.0) | |
1 ~ 2 | 45,244 | 884 (23.3) | 44,360 (72.5) | |
≥ 3 | 17,728 | 2792 (73.6) | 14,936 (24.4) | |
Missing | 37,440 | 2312 | 35,128 | |
BMI, kg/m2 | ||||
75,274 (73.5) | <.0012 | |||
< 18.5 | 1844 | 94 (2.1) | 1750 (2.5) | |
18.5–22.9 | 31,010 | 1146 (25.9) | 29,864 (42.2) | |
23–24.9 | 18,504 | 1003 (22.7) | 17,501 (24.7) | |
25–29.9 | 20,468 | 1821 (41.1) | 18,647 (26.3) | |
≥ 30 | 3448 | 363 (8.2) | 3085 (4.4) | |
Missing | 27,105 | 1677 | 25,428 | |
Family history | 73,757 (72.0) | .2402 | ||
Yes | 5962 | 324 (7.6) | 5638 (8.1) | |
No | 67,795 | 3935 (92.4) | 63,860 (91.9) | |
Missing | 28,622 | 1845 | 26,777 | |
Personal history | 102,379 (100.0) | .5032 | ||
Yes | 2061 | 130 (2.1) | 1931 (2.0) | |
No | 100,318 | 5974 (97.9) | 94,344 (98.0) | |
Missing | 0 | 0 | 0 | |
Lactation experience | 59,723 (58.3) | <.0012 | ||
Yes | 43,705 | 3008 (88.7) | 40,697 (72.2) | |
No | 16,018 | 383 (11.3) | 15,635 (27.8) | |
Missing | 42,656 | 2713 | 39,943 | |
Oral contraceptive use | 58,960 (57.6) | .4932 | ||
Yes | 7009 | 384 (11.5) | 6625 (11.9) | |
No | 51,951 | 2951 (88.5) | 49,000 (88.1) | |
Missing | 43,419 | 2769 | 40,650 | |
Hormone replacement therapy | 58,938 (57.6) | .1422 | ||
Yes | 6415 | 340 (10.1) | 6075 (10.9) | |
No | 52,523 | 3020 (89.9) | 49,503 (89.1) | |
Missing | 43,441 | 2744 | 40,697 | |
Education level | 49,715 (48.6) | <.0012 | ||
More than middle school | 40,078 | 1077 (37.0) | 39,001 (83.3) | |
Less than middle school | 9637 | 1830 (63.0) | 7807 (16.7) | |
Missing | 52,664 | 3197 | 49,467 | |
Prior mammography screening | 48,003 (46.9) | <.0012 | ||
Yes | 27,876 | 1181 (43.4) | 26,695 (59.0) | |
No | 20,127 | 1542 (56.6) | 18,585 (41.0) | |
Missing | 54,376 | 3381 | 50,995 | |
Presence of symptoms | 102,379 (100.0) | <.0012 | ||
Asymptomatic | 21,404 | 1067 (17.5) | 20,337 (21.1) | |
Symptomatic | 80,975 | 5037 (82.5) | 75,938 (78.9) | |
Palpation of the tumor | 69,580 (68.0) | .0092 | ||
Yes | 55,523 | 3321 (81.4) | 52,202 (79.7) | |
No | 14,057 | 759 (18.6) | 13,298 (20.3) | |
Missing | 32,799 | 2024 | 30,775 | |
Breast surgery | 102,379 (100.0) | <.0012 | ||
Mastectomy | 46,713 | 3798 (62.2) | 42,915 (44.6) | |
BCS | 55,666 | 2306 (37.8) | 53,360 (55.4) | |
Axilla surgery | 102,378(100.0) | <.0012 | ||
Sentinel lymph node biopsy | 29,857 | 1899 (31.1) | 27,958 (29.0) | |
Axillary dissection | 64,368 | 3669 (60.1) | 60,699 (63.0) | |
No surgery | 8153 | 536 (8.8) | 7617 (7.9) | |
Missing | 1 | 0 | 1 | |