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Table 6 The univariate and multivariate analyses on prognostic factors in the S-MPESCC group

From: Comparison of clinicopathological features and prognostic significance between synchronous multiple primary and solitary esophageal squamous cell carcinomas

Variable

Univariate analysis

Multivariate analysis

P

HR (95%CI)

P

Age

0.327

-

-

  < 60

  ≥ 60

Smoking

0.020

 

0.017

  No

 

Ref

 

  Yes

 

8.561 (1.475–49.704)

 

Tobacco (Brinkman index)

0.008

 

0.610

Drinking Alcohol

0.137

-

-

  No

  Yes

Total alcohol consumption

0.307

-

-

Location of primary cancer

0.045

 

0.521

  Upper

 

Ref

 

  Middle

 

1.008 (0.102–9.944)

0.995

  Lower

 

1.695(0.148–19.476)

0.672

Operation

0.286

-

-

  Ivor-Lewis

  Mckeown

Length of primary cancer

0.205

-

-

  < 3.75 cm

  ≥ 3.75 cm

pT stage of primary cancer

0.001

 

0.045

  T1-2

 

Ref

 

  T3-4

 

3.968(1.031–15.268)

 

pT stage of multiple cancer

0.018

 

0.153

  T1-4

 

Ref

 

  Tis

 

0.293(0.054–1.580)

 

pN stage

0.028

 

0.906

  N-

 

Ref

 

  N + 

 

1.081(0.295–3.964)

 

Dissection number of lymph nodes

0.137

-

-

 < 24

 ≥ 24

  1. S-MPESCC synchronous multiple primary esophageal squamous cell carcinoma, Tis tumor in situ