Table 5 The univariate and multivariate analyses on prognostic factors in T3–4 group

Age, n (%)

0.851

-

-

  < 60

144(41.7%)

  ≥ 60

201(58.3%)

Smoking, n (%)

0.237

 No

100(29.0%)

 Yes

245(71.0%)

Tobacco (Brinkman index)

0.065

0.285

Drinking Alcohol, n (%)

0.116

-

-

 No

133(38.6%)

 Yes

212(61.4%)

Total alcohol consumption

-

0.023

-

0.078

Location of primary cancer, n (%)

0.029

0.065

 Upper

38(11.0%)

Ref

 Middle

220(63.8%)

2.021(1.110–3.678)

0.021

 Lower

87(25.2%)

1.923(1.003–3.684)

0.049

Operation, n (%)

0.474

-

-

 Ivor-Lewis

47(13.6%)

 Mckeown

298(86.4%)

Length of primary cancer, n (%)

0.342

-

-

 < 3.75 cm

162(47.0%)

 ≥ 3.75 cm

183(53.0%)

Dissection number of lymph nodes, n (%)

0.062

0.030

 < 24

174(50.4%)

Ref

 ≥ 24

171(49.6%)

0.729(0.536–0.991)

Cohort, n (%)

0.033

0.047

 SESCC

316(91.6%)

Ref

 S-MPESCC

29(8.4%)

1.677(1.022–2.752)