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Table 4 The univariate and multivariate analyses of factors associated with LN metastasis in the S-MPESCC group

From: Comparison of clinicopathological features and prognostic significance between synchronous multiple primary and solitary esophageal squamous cell carcinomas

Variables

LNM

P (univariate)

P (multivariate)

No(n = 19)

Yes(n = 31)

Age, n (%)

  

0.833

-

 < 60

8(42.1%)

14(45.2%)

  

 ≥ 60

11(57.9%)

17(54.8%)

  

Smoking, n (%)

 No

4(21.1%)

9(29.0%)

0.532

 

 Yes

15(78.9%)

22(71.0%)

  

Tobacco (Brinkman index)

400

300

0.504

 

Drinking Alcohol, n (%)

  

0.238

-

 No

3(15.8%)

11(35.5%)

  

 Yes

16(84.2%)

20(64.5%)

  

Total alcohol consumption, drinks

500

375

0.162

-

Location of primary cancer, n (%)

  

0.156

-

 Upper

2(10.5%)

1(3.2%)

  

 Middle

14(73.7%)

18(58.1%)

  

 Lower

3(15.8)

12(38.7%)

  

Operation, n (%)

  

1.498

 

 Ivor-Lewis

1(5.3%)

7(22.6%)

 

-

 Mckeown

18(94.7%)

24(77.4%)

  

Length of primary cancer, n (%)

  

0.079

0.220

 < 3.75 cm

14(73.7%)

15(48.4%)

  

  ≥ 3.75 cm

5(26.3%)

16(51.6%)

  

pT stage of primary cancer, n (%)

  

 < 0.001

0.023

 T1

10(52.6%)

2(6.5%)

  

 T2

5(26.3%)

4(12.9%)

  

 T3

2(10.5%)

13(41.9%)

  

 T4

2(10.5%)

12(38.7%)

  

pT stage of multiple cancer, n (%)

  

0.042

0.138

 T1-4

11(57.9%)

26(83.9%)

  

 Tis

8(42.1%)

5(16.1%)

  

Dissection number of lymph nodes, n (%)

  

0.109

0.038

 < 24

13(68.4%)

14(45.2%)

  

 ≥ 24

6(31.6%)

17(54.8%)

  
  1. LN lymph node, LNM lymph node metastasis, S-MPESCC synchronous multiple primary esophageal squamous cell carcinoma, Tis tumor in situ, 1 Drink = 12 g ethanol