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Table 2 The univariate and multivariate analyses of factors associated with LN metastasis for all patients

From: Comparison of clinicopathological features and prognostic significance between synchronous multiple primary and solitary esophageal squamous cell carcinomas

Variables

LNM

P (univariate)

P (multivariate)

No(n = 308)

Yes(n = 259)

Age, n (%)

  

0.300

-

 < 60

127(41.2%)

118(45.6%)

  

 ≥ 60

181(58.8%)

141(54.4%)

  

Smoking, n (%)

 No

99(32.1%)

71(27.4%)

0.221

 

 Yes

209(67.9%)

188(72.6%)

  

Tobacco (Brinkman index)

400

400

0.243

 

Drinking Alcohol, n (%)

  

0.273

-

 No

122(39.6%)

91(35.1%)

  

 Yes

186(60.4%)

168(64.9%)

  

Total alcohol consumption, drinks

250

250

0.119

-

Location of primary cancer, n (%)

  

0.038

0.088

 Upper

37(12.0%)

26(10.0%)

  

 Middle

210(68.2%)

158(61.0%)

  

 Lower

61(19.8%)

75(29.0%)

  

Operation, n (%)

  

0.743

-

Ivor-Lewis

33(10.7%)

30(11.6%)

  

Mckeown

275(89.3%)

229(88.4%)

  

Length of primary cancer, n (%)

  

0.088

0.547

 < 3.75 cm

193(62.7%)

144(55.6%)

  

 ≥ 3.75 cm

115(37.3%)

115(44.4%)

  

pT stage of primary cancer, n (%)

  

 < 0.001

 < 0.001

 T1

80(26.0%)

22(8.5%)

  

 T2

71(23.1%)

49(18.9%)

  

 T3

85(27.6%)

90(34.7%)

  

 T4

72(23.4%)

98(37.8%)

  

Dissection number of lymph nodes, n (%)

  

 < 0.001

0.002

 < 24

191(62.0%)

120(46.3%)

  

 ≥ 24

117(38.0%)

139(53.7%)

  

Cohort, n (%)

  

0.015

0.010

 SESCC

289(93.8%)

228(88.0%)

  

 S-MPESCC

19(6.2%)

31(12.0%)

  
  1. LNM lymph node metastasis, S-MPESCC synchronous multiple primary esophageal squamous cell carcinoma, SESCC single esophageal squamous cell carcinoma, 1 Drink = 12 g ethanol