Table 2 Preoperative treatment regimens, response rates, and treatment related adverse effects in the PCIT group and PCT group
Preoperative treatment characteristics | PCIT group (n = 25) | PCT group (n = 137) | p-value |
|---|---|---|---|
RECIST Criteria (version 1.1)a | Â | Â | 0.151 |
  Partial response | 9(36.0) | 25(18.2) |  |
  Stable disease | 14(56.0) | 103(75.2) |  |
  Progressive disease | 1(4.0) | 2(1.5) |  |
Tumor regression grade (TRG) | Â | Â | 0.030 |
  0 | 5 (21.7) | 10 (7.6) |  |
  1 | 3 (13.0) | 15 (11.5) |  |
  2 | 12 (52.2) | 52 (39.7) |  |
  3 | 3 (13.0) | 54 (41.2) |  |
Preoperative treatment regimen | Â | Â | 0.074 |
  One-drug regimen | 1(4.0) | 0(0) |  |
  Two-drug regimen | 21(84.0) | 109(79.6) |  |
  Three-drug regimen | 3(12.0) | 28(20.4) |  |
Preoperative treatment cycle | Â | Â | 0.597 |
  ≤4 | 16(64.0) | 95(69.3) |  |
  >4 | 9(36.0) | 42(30.7) |  |
Adverse event(AE)b | Â | Â | 0.088 |
  Grade 0 | 11(45.8) | 29(22.0) |  |
  Grade 1 | 5(20.8) | 48(36.4) |  |
  Grade 2 | 7(29.2) | 35(26.5) |  |
  Grade 3 | 1(4.2) | 16(12.1) |  |
  Grade 4 | 0(0) | 4(3.0) |  |