Table 3 Univariate and multivariate disease-free survival analysis

Age(≥ 60 vs < 60)

0.85

0.47–1.51

0.484

Sex (M vs F)

1.35

0.72–2.52

0.377

Differentiation (Poor vs Well)

1.93

1.08–3.45

0.044

Tumor invasion (T1-2 vs T3-4)

0.15

0.08–0.28

0.001

4.20

0.98–18.00

0.053

Lymph node (N0 vs N +)

0.08

0.04–0.14

 < 0.001

3.56

1.87–4.25

0.038

TNM stage (I-II vs III)

0.21

0.12–0.37

 < 0.001

4.88

2.03–11.71

0.000

Ki-67 index (Low vs High)

0.76

0.40–1.45

0.402

Her-2 (0 vs Low)

0.90

0.47–1.70

0.741