Table 2 Univariate and multivariate Cox regression analyses of the factors predict progression-free interval in PCa

T stage(T3&T4 vs T2)

492

3.785 (2.140-6.693)

< 0.001

1.444 (0.690-3.023)

0.330

N stage(N1 vs N0)

426

1.946 (1.202-3.150)

0.007

0.981 (0.568-1.695)

0.945

M stage(M1 vs M0)

458

3.566 (0.494-25.753)

0.208

Gleason score(9&10 vs 6&7&8)

499

4.590 (3.038-6.934)

< 0.001

2.375 (1.382-4.082)

0.002

PSA(ng/ml)(≥4 vs < 4)

442

4.196 (2.095-8.405)

< 0.001

1.814 (0.813-4.050)

0.146

Age(> 60 vs ≤ 60)

499

1.302 (0.863-1.963)

0.208

Primary therapy outcome(PD&SD&PR vs CR)

438

6.627 (4.337-10.126)

< 0.001

3.586 (2.026-6.348)

< 0.001

Race(Asian&White vs Black&African American)

484

1.728 (0.866-3.448)

0.120

Residual tumor(R1&R2 vs R0)

468

2.365 (1.566-3.570)

< 0.001

0.928 (0.546-1.578)

0.783

Zone of origin(Overlapping & Multiple Zones vs Peripheral &Central &Transition Zone)

275

1.318 (0.819-2.123)

0.256

MAPK8IP2(High vs Low)

499

2.134 (1.392-3.272)

< 0.001

1.690 (1.045-2.733)

0.032