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Fig. 3 | BMC Cancer

Fig. 3

From: PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry

Fig. 3

Performance of Polygenic Risk Scores (PRSs) Constructed from Different Ancestral Backgrounds in African Ancestry Group in ELLIPSE Consortium. ROC curve for genetic prediction of PrCa risk in ELLIPSE Consortium African ancestry group (n = 4,533) using: A PRSs constructed from 10 African ancestry-specific variants with age and family history. B PRSs constructed from 7 European ancestry-specific variants with age and family history. C PRSs constructed from 14 trans-ancestry specific variants with age and family history. Quantile plot of PRS constructed from: 10 African ancestry-specific variants D and 7 European ancestry-specific variants (E) and respective odds of prostate cancer

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