Table 1 Baseline patient characteristics
Characteristic | Pre-Pandemic Cohort (n = 36,362) | COVID-19 Cohort (n = 17,545) | Standardized Difference |
|---|---|---|---|
Sex | |||
Female, n (%) | 17,675 (48.6%) | 8,886 (50.6%) | 0.041 |
Age at index date (cancer diagnosis) | |||
Mean (SD) | 59.01 (12.18) | 58.54 (12.03) | 0.039 |
Median (IQR) | 59 (51–67) | 59 (51–67) | 0.038 |
Cancer type, n(%) | |||
Breast | 8,580 (23.6%) | 4,528 (25.8%) | 0.051 |
Colorectal | 5,698 (15.7%) | 2,833 (16.1%) | 0.013 |
Head and neck | 1,646 (4.5%) | 793 (4.5%) | 0.00 |
Hematologic | 5,977 (16.4%) | 2,882 (16.4%) | 0.00 |
Lung | 6,770 (18.6%) | 3,103 (17.7%) | 0.024 |
Prostate | 7,691 (21.2%) | 3,406 (19.4%) | 0.043 |
Cancer stage, n(%) | |||
Metastatic | 6,001 (16.5%) | 1,678 (9.6%) | 0.21* |
Non-metastatic | 21,799 (59.9%) | 5,839 (33.3%) | 0.56* |
Missing | 8,562 (23.5%) | 10,028 (57.2%) | 0.73* |
Income quintile, n(%) | |||
1 | 7,148 (19.7%) | 3,395 (19.4%) | 0.008 |
2 | 7,517 (20.7%) | 3,527 (20.1%) | 0.014 |
3 | 7,230 (19.9%) | 3,515 (20.0%) | 0.004 |
4 | 6,955 (19.1%) | 3,429 (19.5%) | 0.011 |
5 | 7,404 (20.4%) | 3,627 (20.7%) | 0.008 |
Missing | 108 (0.3%) | 52 (0.3%) | 0.00 |
ON-Marg material deprivation index, n(%) | |||
1 | 7,810 (21.5%) | 3,877 (22.1%) | 0.013 |
2 | 7,383 (20.3%) | 3,580 (20.4%) | 0.009 |
3 | 7,063 (19.4%) | 3,444 (19.6%) | 0.003 |
4 | 7,011 (19.3%) | 3,286 (18.7%) | 0.017 |
5 | 6,807 (18.7%) | 3,215 (18.3%) | 0.011 |
Missing | 288 (0.8%) | 143 (0.8%) | 0.01 |
ON-Marg dependency index, n(%) | |||
1 | 6,471 (17.8%) | 3,284 (18.7%) | 0.026 |
2 | 6,494 (17.9%) | 3,127 (17.8%) | 0.00 |
3 | 6,558 (18.0%) | 3,251 (18.5%) | 0.011 |
4 | 6,968 (19.2%) | 3,242 (18.5%) | 0.02 |
5 | 9,583 (26.4%) | 4,498 (25.6%) | 0.018 |
Missing | 288 (0.8%) | 143 (0.8%) | 0.01 |
ON-Marg ethnic concentration index, n(%) | |||
1 | 7,543 (20.7%) | 3,621 (20.6%) | 0.008 |
2 | 7,108 (19.5%) | 3,476 (19.8%) | 0.005 |
3 | 6,822 (18.8%) | 3,164 (18.0%) | 0.015 |
4 | 6,887 (18.9%) | 3,323 (18.9%) | 0.001 |
5 | 7,714 (21.2%) | 3,818 (21.8%) | 0.015 |
Missing | 288 (0.8%) | 143 (0.8%) | 0.01 |
ON-Marg residential instability index, n(%) | |||
1 | 6,557 (18.0%) | 3,329 (19.0%) | 0.014 |
2 | 6,779 (18.6%) | 3,319 (18.9%) | 0.005 |
3 | 7,146 (19.7%) | 3,386 (19.3%) | 0.003 |
4 | 6,982 (19.2%) | 3,350 (19.1%) | 0.006 |
5 | 8,610 (23.7%) | 4,018 (22.9%) | 0.018 |
Missing | 288 (0.8%) | 143 (0.8%) | 0.01 |
Collective Co-morbidity burden (ADGs), n(%) | |||
0–4 ADGs | 9,531 (26.2%) | 4,690 (26.7%) | 0.012 |
5–9 ADGs | 18,497 (50.9%) | 8,998 (51.3%) | 0.022 |
10 + ADGs | 8,334 (22.9%) | 3,857 (22.0%) | 0.008 |
Persons with medical conditions associated with frailty), n(%) | |||
No | 33,574 (92.3%) | 16,370 (93.3%) | 0.038 |
Yes | 2,788 (7.7%) | 1,175 (6.7%) | 0.038 |
Resource utilization bands, n(%) | |||
0 | 45 (0.1%) | 16 (0.1%) | 0.01 |
1 | 185 (0.5%) | 110 (0.6%) | 0.016 |
2 | 1,627 (4.5%) | 824 (4.7%) | 0.011 |
3 | 17,205 (47.3%) | 8,500 (48.4%) | 0.023 |
4 | 9,485 (26.1%) | 4,591 (26.2%) | 0.002 |
5 | 7,815 (21.5%) | 3,504 (20.0%) | 0.038 |