Fig. 5

Average value of clustering between samples between 9 mice. Paired comparison of the mean distribution of Variant Allele Frequency subsets between primary tongue tumor cells and lymph node metastatic tumor cells in 9 mice: 1–3 dysplastic mice, 4–6 mice without lymph node metastasis, 7–9 mice with lymph node metastasis. Variant Allele Frequency subgroups were obtained by clustering the CCF values of tumor cells in different parts of each mouse. The Variant Allele Frequency subgroups of each mouse correspond to a specific color and shape