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Table 6 Correlations between maximum acute genitourinary (GU) toxicity grade, maximum acute gastrointestinal (GI) toxicity grade, maximum fatigue score, and serum concentrations of IL-6 and TGF-β1 in patients with prostate cancer treated with radiotherapy

From: Circulating levels of IL-6 and TGF-β1 in patients with prostate cancer undergoing radiotherapy: associations with acute radiotoxicity and fatigue symptoms

Variable 1

Variable 2

Correlation coefficient

p

Maximum GU toxicity grade

Maximum GI toxicity grade

0.09

0.594

Maximum GU toxicity grade

Maximum fatigue score

0.15

0.353

Maximum GI toxicity grade

Maximum fatigue score

0.26

0.117

Pretreatment IL-6 concentration

Maximum GU toxicity grade

0.31

0.054

Pretreatment IL-6 concentration

Maximum GI toxicity grade

0.10

0.548

Pretreatment IL-6 concentration

Maximum fatigue score

0.35

0.032

IL-6 concentration after the 25th fraction

Maximum GU toxicity grade

0.21

0.199

IL-6 concentration after the 25th fraction

Maximum GI toxicity grade

0.08

0.640

IL-6 concentration after the 25th fraction

Maximum fatigue score

0.29

0.069

Pretreatment TGF-β1 concentration

Maximum GU toxicity grade

0.34

0.036

Pretreatment TGF-β1 concentration

Maximum GI toxicity grade

0.06

0.724

Pretreatment TGF-β1 concentration

Maximum fatigue score

0.19

0.257

TGF-β1 concentration after the 25th fraction

Maximum GU toxicity grade

0.31

0.052

TGF-β1 concentration after the 25th fraction

Maximum GI toxicity grade

0.10

0.535

TGF-β1 concentration after the 25th fraction

Maximum fatigue score

0.29

0.074