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Table 2 Correlation of PD-L1 expression, CD8+ TIL levels and clinical features

From: Programmed death ligand 1 and tumor-infiltrating CD8+ T lymphocytes are associated with the clinical features in meningioma

Clinical features

PD-L1 expression

CD8+ TIL levels

 

Low

High

P value

Low

High

P value

Age (years)

  

0.755

  

0.751

  ≤ 46

24

23

 

24

23

 

 >46

22

24

 

25

21

 

Gender

  

0.848

  

0.642

 Male

10

11

 

12

9

 

 Female

36

36

 

37

35

 

Smoking

  

0.797

  

0.491

 No

40

40

 

41

39

 

 Yes

6

7

 

8

5

 

Drinking

  

0.450

  

0.607

 No

39

37

 

41

35

 

 Yes

7

10

 

8

9

 

Preoperative symptoms

 Visual impairment

  

0.757

  

0.610

  No

36

38

 

38

36

 

  Yes

10

9

 

11

8

 

 Headache

  

0.067

  

0.982

  No

41

35

 

40

36

 

  Yes

5

12

 

9

8

 

 Limb weakness

  

0.450

  

0.272

  No

39

37

 

38

38

 

  Yes

7

10

 

11

6

 

 Epilepsy

  

0.486

  

0.164

  No

43

41

 

42

42

 

  Yes

3

6

 

7

2

 

Tumor volume (cm3)

  

0.0006

  

0.171

 ≤ 42.89

32

16

 

22

26

 

 >42.89

14

31

 

27

18

 

Peritumoral brain edema

  

0.442

  

0.0001

  No

30

27

 

21

36

 

  Yes

16

20

 

28

8

 

Tumor sites

  

0.558

  

0.496

 Convexity

6

9

 

10

5

 

 Skull base

35

31

 

33

33

 

 Ventricle

5

7

 

6

6

 

WHO grade

  

0.224

  

0.318

 I

30

24

 

27

27

 

 II

7

14

 

14

7

 

 III

9

9

 

8

10

 
  1. The median value of PD-L1 and CD8+ TIL expression was used as cutoff points to divide the cohort into groups with low and high