Fig. 2
The association among the PD-L1 expression, CD8+ TIL levels, and clinical features. a The PD-L1 expression was significantly correlated with the tumor volume. b Cases with larger tumor volume indicated higher PD-L1 expression in IHC staining relative to those with a smaller volume. Scale bar = 20 μm. c The CD8+ TIL levels were not associated with the tumor volume. d The number of CD8+ TILs in IHC staining was not significantly different between the samples with small and large tumor volumes. Scale bar = 20 μm. e The CD8+ TIL levels were significantly associated with PTBE. f The PD-L1 expression was not associated with PTBE. g The number of CD8+ TILs in IHC staining was significantly higher in cases without PTBE than in those with PTBE. The red arrows in MRI images indicated a meningeal tail sign and PTBE, respectively. Scale bar = 20 μm. IHC, immunohistochemistry; PD-L1, programmed death ligand 1; TILs, tumor-infiltrating lymphocytes; TV, tumor volume; T1CE, T1WI contrast-enhancement; T2, T2WI; PTBE, peritumoral brain edema