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Fig. 8 | BMC Cancer

Fig. 8

From: HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways

Fig. 8

In CAOV3 and SKOV3 ovarian cancer cell lines, HERPUD1 inhibits PI3K/AKT and p38MAPK signaling pathways. a, b After knocking down HERPUD1, the phosphorylation ratio of PI3K / AKT / mTOR pathway-related nodal proteins (PI3K / AKT / mTOR) and p38MAPK pathway-related nodal protein (p38) increased. Due to the different transfer conditions, the antibody incubation was performed after the membrane was cut. Data are presented as the mean ± SEM (n = 3 per group), *P < 0.05, **P < 0.01,*** P < 0.001 vs. the NC group

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