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Fig. 1 | BMC Cancer

Fig. 1

From: HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways

Fig. 1

The expression of HERPUD1 and Lewis y in different ovarian tissues, and the expression of HERPUD1 is regulated by Lewis y. a The expression of HERPUD1 and Lewis y in different ovarian tissues (× 200).i.v: epithelial ovarian cancer; ii, vi: epithelial borderline ovarian tumor; iii, vii: benign epithelial ovarian tumor; iv, viii: normal ovary. b The relative expression of HERPUD1 and FUT1 in ovarian cancer patients of different FIGO stages in GEPIA database. c Analysis of the relationship between the expression of HERPUD1, Lewis y and the prognosis of ovarian cancer. d After transfection with α1,2-FUT1 plasmid, the expression of Lewis y increased was detected by immunocytochemistry. e, f Western blotting showed that after overexpressing Lewis y, HERPUD1 protein expression increased. Due to the different transfer conditions, the antibody incubation was performed after the membrane was cut. Data are presented as the mean ± SEM (n = 3 per group), *P < 0.05, **P < 0.01,*** P < 0.001 vs. the NC group

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